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[D-Pro194]-IL-1 b (193-195) (human)

Name
[D-Pro194]-IL-1 b (193-195) (human)
Molecular structural formula
Purity
≥95%
CAS Number
117027-34-6
Formula
C15H28N4O5
MW
344.41
Target
Interleukin Related
Sequence
Lys-D-Pro-Thr
Sequence Shortening
L-{D-Pro}-T
InChIKey
LOGFVTREOLYCPF-KXNHARMFSA-N
Solubility in DMSO
100 mg/mL
References
[1]. Takahiro Tsuruki, et al. Mechanism of the protective effect of intraperitoneally administered agonists for formyl peptide receptors against chemotherapy-induced alopecia. Biosci Biotechnol Biochem. 2007 May;71(5):1198-202. [2]. Y Uehara, et al. Central administration of Lys-D-Pro-Thr, an interleukin-1 beta 193-195 analogue, stimulates feeding in rats. Neuropeptides. 1991 May;19(1):9-11.
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[D-Pro194]-IL-1 b (193-195) (human), an IL-1beta analogue, is a potent IL-1 inhibitor. Lys-D-Pro-Thr inhibits the protective effects of IL-1 beta.